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Loubina Fazal Selected Research

EPAC1 inhibitor AM-001

10/2019Identification of a pharmacological inhibitor of Epac1 that protects the heart against acute and chronic models of cardiac stress.

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Loubina Fazal Research Topics

Disease

4Heart Diseases (Heart Disease)
01/2020 - 06/2014
4Cardiomegaly (Heart Hypertrophy)
10/2019 - 01/2012
4Inflammation (Inflammations)
10/2019 - 06/2012
4Fibrosis (Cirrhosis)
10/2019 - 06/2012
4Hypertrophy
10/2019 - 01/2012
4Heart Failure
10/2017 - 01/2015
4Hypertension (High Blood Pressure)
01/2016 - 01/2012
2Hyperaldosteronism (Conn Syndrome)
03/2016 - 06/2012
1Mitochondrial Diseases (Mitochondrial Disease)
01/2020
1Ventricular Dysfunction
01/2020
1Myocardial Infarction
12/2017
1Cardiomyopathies (Cardiomyopathy)
10/2017
1Infarction (Infarctions)
02/2017
1Reperfusion Injury
02/2017
1Myocardial Ischemia (Ischemic Heart Diseases)
02/2017
1Left Ventricular Dysfunction
03/2016
1Cardiovascular Diseases (Cardiovascular Disease)
06/2014
1Microvascular Rarefaction
08/2013

Drug/Important Bio-Agent (IBA)

5AldosteroneIBA
03/2016 - 01/2012
3Proteins (Proteins, Gene)FDA Link
02/2017 - 06/2012
3Angiotensin IIIBA
01/2016 - 06/2012
2Adrenergic Receptors (Adrenergic Receptor)IBA
10/2019 - 01/2015
2Isoproterenol (Isoprenaline)FDA LinkGeneric
10/2019 - 03/2016
2Galectin 3 (LGALS3)IBA
03/2016 - 06/2012
2Atrial Natriuretic Factor (ANF)IBA
08/2013 - 01/2012
2Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA
08/2013 - 06/2012
1Monoamine Oxidase (MAO)IBA
01/2020
1AldehydesIBA
01/2020
14-hydroxy-2-nonenal (4-hydroxynonenal)IBA
01/2020
1EPAC1 inhibitor AM-001IBA
10/2019
1Carrier Proteins (Binding Protein)IBA
10/2019
1salicylhydroxamic acid (SHAM)IBA
12/2017
1Angiogenesis Inducing Agents (Angiogenesis Factor)IBA
10/2017
1Placenta Growth FactorIBA
10/2017
1Tyrosine (L-Tyrosine)FDA Link
10/2017
1N 30IBA
10/2017
1Cyclic AMP (AMP, Cyclic)IBA
02/2017
1Canrenoic Acid (Potassium Canrenoate)IBA
03/2016
1Mineralocorticoid Receptor AntagonistsIBA
03/2016
1citrus pectinIBA
03/2016
1CalcineurinIBA
01/2015
1Calcium-Calmodulin-Dependent Protein KinasesIBA
01/2015
1Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA
01/2015
1Cytochrome P-450 CYP11B2 (CYP11B2)IBA
08/2013
1ReninIBA
08/2013
1Messenger RNA (mRNA)IBA
06/2012
1Brain Natriuretic Peptide (Natrecor)FDA Link
06/2012
1Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
06/2012
1Bone Morphogenetic Protein 4IBA
06/2012
1Galectins (Galectin)IBA
06/2012
1OsteopontinIBA
06/2012
1Natriuretic PeptidesIBA
01/2012
1Myosin Heavy Chains (Myosin Heavy Chain)IBA
01/2012

Therapy/Procedure

1Drug Therapy (Chemotherapy)
10/2019
1Ligation
12/2017
1Subcutaneous Injections
03/2016